THE FORMATION ALGORITHM OF SOCIAL-PROJECTED COMPETENCES OF EXPERTS IN ECOLOGY



CDK4/6 inhibitor-SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb and inducing G1 cell cycle arrest

Abstract Background Cell cycle dysregulation is common in human malignancies, and CDK4/6 inhibitors targeting cell cycle have potential antitumor activity.SHR6390 is a novel small molecule inhibitor specifically targeting the CDK4/6 pathway.However, the role of SHR6390 in esophageal squamous cell carcinoma (ESCC) remains unknown, which will be inve

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